How does a biopsy needle work




















Ask your doctor how long you can expect to wait. Your health care team may apply a bandage over the area where the needle was inserted. You may be asked to apply pressure to the bandage for several minutes to ensure there is minimal bleeding. In most cases, you can leave when your needle biopsy procedure is completed. Whether you can leave right away or whether you'll need to stay for observation depends on what part of your body was biopsied.

In some cases, your health care team may want to observe you for a few hours to ensure you won't have complications from your biopsy. If you received an IV sedative or general anesthetic, you'll be taken to a comfortable place to relax while the medication wears off.

Plan to take it easy for the rest of the day. Protect the area where you received the needle biopsy by keeping the bandage in place for as long as instructed. You may feel some mild pain or discomfort in the area, but this should go away in a day or two. Doctors who specialize in studying cells and tissue samples for signs of disease pathologists will study the biopsy sample in the laboratory and make a diagnosis.

These doctors will create a pathology report for your doctor. Once your doctor receives the report, he or she will contact you with the results. You can request a copy of your pathology report from your doctor.

Pathology reports are usually filled with technical terms, so you may find it helpful to have your doctor review the report with you. The results of your needle biopsy will determine the next steps in your medical care.

Talk with your doctor about what your results mean for you. Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions. Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. This content does not have an English version. An endoscopy procedure involves inserting a long, flexible tube endoscope down your throat and into your esophagus.

A tiny camera on the end of the endoscope lets your doctor examine your esophagus, stomach and the beginning of your small intestine duodenum. During endoscopy, your doctor uses a thin, flexible tube endoscope with a light on the end to see structures inside your body. Special tools are passed through the tube to take a small sample of tissue to be analyzed.

What type of endoscopic biopsy you undergo depends on where the suspicious area is located. Tubes used in an endoscopic biopsy can be inserted through your mouth, rectum, urinary tract or a small incision in your skin. Examples of endoscopic biopsy procedures include cystoscopy to collect tissue from inside your bladder, bronchoscopy to get tissue from inside your lung and colonoscopy to collect tissue from inside your colon.

Depending on the type of endoscopic biopsy you undergo, you may receive a sedative or anesthetic before the procedure. During needle biopsy, a long, thin needle is inserted through the skin and into the suspicious area.

Cells are removed and analyzed to see if they are cancerous. During a needle biopsy, your doctor uses a special needle to extract cells from a suspicious area. A needle biopsy is often used on tumors that your doctor can feel through your skin, such as suspicious breast lumps and enlarged lymph nodes.

When combined with an imaging procedure, such as X-ray, needle biopsy can be used to collect cells from a suspicious area that can't be felt through the skin.

Image-guided biopsy. Image-guided biopsy combines an imaging procedure — such as X-ray, computerized tomography CT , magnetic resonance imaging MRI or ultrasound — with a needle biopsy. Image-guided biopsy allows your doctor to access suspicious areas that can't be felt through the skin, such as abnormalities on the liver, lung or prostate. Using real-time images, your doctor can make sure the needle reaches the correct spot.

During a punch biopsy, a doctor uses a special circular blade to remove deeper layers of skin for testing. Depending on the size, stitches may be necessary to close the wound. A skin cutaneous biopsy removes cells from the surface of your body. A skin biopsy is used most often to diagnose skin conditions, including melanoma and other cancers. What type of skin biopsy you undergo will depend on the type of cancer suspected and the extent of the suspicious cells.

Skin biopsy procedures include:. If the cells in question can't be accessed with other biopsy procedures or if other biopsy results have been inconclusive, your doctor may recommend a surgical biopsy. During a surgical biopsy, a surgeon makes an incision in your skin to access the suspicious area of cells. Examples of surgical biopsy procedures include surgery to remove a breast lump for a possible breast cancer diagnosis and surgery to remove a lymph node for a possible lymphoma diagnosis.

Surgical biopsy procedures can be used to remove part of an abnormal area of cells incisional biopsy. Or surgical biopsy may be used to remove an entire area of abnormal cells excisional biopsy. You may receive local anesthetics to numb the area of the biopsy. For any type of CNB, a thin needle will be used to put in medicine to numb your skin. The biopsy needle is put into the breast tissue through this cut to remove the tissue sample. You might feel pressure as the needle goes in.

Again, imaging tests may be used to guide the needle to the right spot. Typically, a tiny tissue marker also called a clip is put into the area where the biopsy is done. This marker shows up on mammograms or other imaging tests so the exact area can be located for further treatment if needed or follow up. It can stay in place during MRIs, and it will not set off metal detectors.

Once the tissue is removed, the needle is taken out. Typically, several samples of tissue are collected from around the lesion. After this sampling, the needle will be removed. If a surgical biopsy is being performed, a wire may be inserted into the suspicious area as a guide for the surgeon. Once the biopsy is complete, pressure will be applied to stop any bleeding, and the skin will be covered with a dressing or bandage.

Depending on the type of biopsy performed, you may be able to return home immediately after the procedure. This procedure is usually completed within one hour. You may be required to stay in an area for observation for several hours after the biopsy depending on the type of biopsy performed. In a needle biopsy, you will feel a small sharp pinch at the site of the biopsy.

In an open or closed biopsy that requires surgery, you will be given anesthesia to help with the pain. When you receive the local anesthetic to numb the skin, you will feel a slight pin prick from the needle. You may feel some pressure when the biopsy needle is inserted. The area will become numb within a short time.

You may receive a mild sedative prior to the biopsy. If needed, you may receive sedation or relaxation medication intravenously during the procedure. You may feel sore at the area of the biopsy for a few days. Your doctor can prescribe pain relief medication if you have significant pain from the biopsy. Aftercare instructions vary.

However, you generally may remove your bandage one day after the procedure, and you may bathe or shower as normal. After the tissue is collected, it is sent to a laboratory for analysis. A pathologist will examine the biopsy tissue under a microscope. A full report from the pathologist will be sent to your doctor in a few days. If you underwent a breast biopsy, it is likely the radiologist will discuss your results with you. This visit may include a physical check-up, imaging exam s , and blood tests.

During your follow-up visit, tell your doctor if you have noticed any side effects or changes. Generally a biopsy procedure is safe and causes minimal injury. Complications that may result from biopsies include:. In some cases, the amount of tissue obtained from a needle biopsy may not be sufficient and the biopsy may have to be repeated.

This may be particularly true with trying to make a diagnosis of lymphoma. Rarely, less invasive breast biopsy procedures may be unable to detect some lesions or determine the extent of disease present.

If the diagnosis remains uncertain after a technically successful procedure, surgical biopsy will usually be necessary. Any imaging-guided procedure will not be able to be used unless the area of abnormality can be seen. Some lesions, such as clustered calcifications on mammography are not as clearly shown with ultrasound as they are with mammography.

Therefore, stereotactic biopsy is usually used in breast imaging to biopsy calcifications. Fluoroscopy sometimes will not be able to locate chest nodules, and CT will be used for guidance. Your radiologist will use the image guidance best suited to biopsy the area in question. Please type your comment or suggestion into the text box below. Note: we are unable to answer specific questions or offer individual medical advice or opinions.

Some imaging tests and treatments have special pediatric considerations. The teddy bear denotes child-specific content. Please contact your physician with specific medical questions or for a referral to a radiologist or other physician.

To locate a medical imaging or radiation oncology provider in your community, you can search the ACR-accredited facilities database. This website does not provide cost information. The costs for specific medical imaging tests, treatments and procedures may vary by geographic region. Web page review process: This Web page is reviewed regularly by a physician with expertise in the medical area presented and is further reviewed by committees from the Radiological Society of North America RSNA and the American College of Radiology ACR , comprising physicians with expertise in several radiologic areas.

Outside links: For the convenience of our users, RadiologyInfo. Toggle navigation. What are biopsies? What are some common uses of the procedure? How should I prepare? What does the equipment look like? How does the procedure work? How is the procedure performed?



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